ea0056p605 | Obesity | ECE2018
Rafey Mohammed Faraz
, Fang Clarissa Ern Hui
, Ioana Iulia
, Griffin Helena
, Hynes Mary
, O'brien Timothy
, Mcanena Oliver
, O'shea Paula
, Collins Chris
, Finucane Francis Martin
Background: Bariatric surgery is known to dramatically increase insulin sensitivity in severely obese adults. However quantifying insulin sensitivity in these patients with methods such as the hyperinsulinaemic euglycaemic clamp is technically challenging. The leptin to adiponectin ratio (LAR) has previously been validated as a measure of whole body insulin sensitivity. Leptin is a known mediator of metabolic and cardiovascular complications of obesity. Adiponectin has anti-at...